Fig 1: LFQ intensity of CDH2, ARVCF, Cx50, and Cx46 in the suture and suture adjacent regions. LFQ intensities of CDH2, ARVCF, Cx50, and Cx46 were Log2 transformed, and Student t-tests were performed. The abundance of ARVCF (A) and CDH2 (B) increases in the suture regions (white bars) compared with adjacent regions (black bars) in both anterior and posterior regions of the lens. The abundance of Cx50 (C) decreased in the suture regions (white bars) compared with adjacent regions (black bars) in the anterior of the lens. The same trend was also detected for Cx46, but the difference did not reach statistical significance. Both Cx50 (C) and Cx46 (D) in posterior region did not significantly change between the two LCM captured regions. *P < 0.05, **P < 0.005.